Generic Name: Nitrofurantoin 100mg.
Manufacturer Name: Incepta Pharmaceuticals Ltd.
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Indications
An antibiotic that fights bacteria is called Nintoin 100. It is applied to the treatment and avoidance of simple urinary tract infections. It functions by eradicating the bacteria responsible for the disease. However, it won't help with viral infections. The doctor's recommended dose and duration for taking Nintoin 100 should be followed.
Pharmacology
Nitrofurantoin is an antibacterial agent that works particularly well for infections of the urinary tract. Extremely solvent in urination, nitrofurantoin may give poop a brown hue. Ribosomal proteins and other macromolecules produced by bacteria are inactivated or altered by nitrofurantoin. It has been demonstrated that nitrofurantoin is effective against pursuing microscopic organisms: Grass-Feeding Aerobes Enterococcus faecalis, Staphylococcus aureus, Streptococcus agalactiae, Gather D streptococci, and Viridans gather streptococci are among the staphylococci that are Coagulase-negative and include Staphylococcus epidermidis. Escherichia coli, Citrobacter amalonaticus, Citrobacter diversus, Citrobacter freundii, Klebsiella oxytoca, and Klebsiella ozaena are examples of Gram-negative Aerobes.
Dosage & Administration
Nitrofurantoin tablet (In adults):
Nitrofurantoin capsule (In adults):
Prophylaxis:
Nitrofurantoin SR capsule:
Genito-urinary surgical prophylaxis:
Nitrofurantoin suspension:
Children: 5-7 mg/kg/day in four divided doses (contraindicated under one month of age). The average dose of Nintoin suspension for pediatric patients is as follows-
Therapy should be continued for one week or for at least 3 days after sterility of the urine is obtained. For long-term suppressive therapy in children, doses as low as 1 mg/kg per 24 hours, given in a single dose or in two divided doses, may be adequate.
Interaction
When taken with Nitrofurantoin, antacids containing Magnesium Trisilicate diminish the rate and degree of absorption of Uricosuric medicines like Probenecid and Sulfinpyrazone and can limit Nitrofurantoin secretion in the renal tubules.
Contraindications
Contraindications include anuria, oliguria, and substantial impairment of renal function. This medication is contraindicated in pregnant women between the ages of 38 and 42 weeks, as well as during labor and delivery. Nitrofurantoin is also contraindicated in patients who have a history of allergy to the drug.
Side Effects
Nausea, headaches, and flatulence are the most common clinical side effects. Diarrhea, dyspepsia, abdominal pain, constipation, emesis, dizziness, and tiredness are some of the less common side effects.
Pregnancy & Lactation
Pregnancy Classification B. In pregnant women, there are no sufficient and well-controlled trials. This medication should only be used during pregnancy if absolutely necessary. Human breast milk has been found to contain trace quantities of nitrofurantoin. Because of the risk of serious side effects from Nitrofurantoin in nursing infants under the age of one month, a choice should be taken on whether to stop breastfeeding or stop taking the drug, taking into account the drug's importance to the mother.
Precautions & Warnings
If acute, sub-acute, or chronic pulmonary reactions occur, Nitrofurantoin should be discontinued. Antacid preparations containing magnesium trisilicate should not be taken while taking Nitrofurantoin.
Storage Conditions
Do not store above 30°C. Keep away from light and out of the reach of children
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